THIS LECTURE COURSE WILL DISCUSS TOPICS SUCH AS NOISE, STOCHASTICITY, ROBUSTNESS, PROPERTIES OF NETWORK MOTIFS, PERMISSIVE AND INSTRUCTIVE SIGNALING, TIMER, MORPHOGEN GRADIENT, SCALING, MODULARITY, MODELING, AND APPLYING THIS KNOWLEDGE TO DESIGN ARTIFICIAL REGULATORY CIRCUITS. THE LECTURES WILL RANGE FROM THEORETICAL ANALYSIS OF CIRCUITS BEHAVIORS TO EXPERIMENTAL SYSTEMS WHERE THESE PRINCIPLES WERE ACTUALLY TESTED.